Dietary vitamin D3 needs to transformed in the liver and in the kidneys into a bio-available form. This process is time-consuming and also less effective during the first week of life and in older laying hens. Therefor instant supply of the bioactive metabolite 25-hydroxyvitamin D3 (25OHD3) allows faster delivery and more efficient uptake of bio-active vitamin D3. This results in a stronger skeleton to manage the rapid gain of body weight and stronger egg shells in the second phase of lay.
Recent research shows that vitamin D3 also has an important immunomodulating effect. It exerts a positive effect on innate and adaptive immune cells and this way improves vaccination efficacy and protects chickens against numerous health challenges (Shojadoost et al, 2021).
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